Reducing inflammation to improve burn injury repair

Chief Investigator:

Professor Allison Cowin

Funding Amount:



University of South Australia


Burns are one of the most common injuries in young children. They cause lifelong scarring and frequently contract as the child gets older, requiring extensive surgical intervention to prevent deformity and contracture. Inflammation is a fundamental component of wound healing, however, excessive inflammation is detrimental and leads to fibrosis and scarring. Therapies currently exist to dampen inflammation in other diseases. Since inflammation plays such a significant role in fibrosis and scarring the use of these existing therapies could rapidly lead to new therapeutic approaches for burns.